13th Conference on Medicinal and Aromatic Plants of Southeast European Countries (CMAPSEEC 2026)

Öznur Diler 1 Pape Cheikh MBAYE1 Kamil Atsatan1
1 Isparta University of Applied Science, Eğirdir Fisheries Faculty, TÜRKİYE
Abstract In the current study, the effects of dietary ethanolic grape seed extract (GSE) on some biochemical parameters, intestinal microflora and histomorphology were investigated in carp ( Cyprinus carpio L.) For this purpose, carp diets supplemented to basal diet at four experimental levels including 0.5%, 1% and 1.5% GSE and an unsupplemented control diet. The experiment was conducted over 45 days in nine plastic tanks with carp juveniles averaging 18 g, using three replicates per treatment and 10 fish per tank. The chemical composition of GSE was determined by HPLC. Phenolic compounds ,the catechin ,epicatechin and gallic acid showed high concentrations in the GSE. Fish fed GSE suplemented diet enhanced some biochemical parameters, intestinal microflora in experimental groups in comparison with the control group. There were significant differences in the level of including total protein and albumin between all treatment groups; however, the activities of ALT (alanin aminotransferaz), AST (aspartat aminotransferaz), levels of fish fed with different doses of GSE were lower than that of the control group (p<0.05). The lactic acid bacteria count increased in fish fed the GSE groups .Histological analyses revealed no liver damage. It was determined that the use of GSE have positive effects on biochemical parameters and intestinal microflora in carp ( Cyprinus carpio L.). In conclusion, the GSE may be used as alternative feed supplement in aquaculture